An enthusiastic writer and learner, developing from Caterpiller to a Beautiful Butterfly. Check out my Social Media profiles to Contact me. Keep in touch folks and read my writeups.

Use of dexamethasone as prophylactic treatment in moderate to severe COVID-19 condition

A Short Review Recommended To Carry Further Research The study proposed was aimed to identify and assess the effect of dexamethasone in mild and moderate cases of COVID-19. Coronavirus disease 2019 (COVID-19) is associated with diffuse lung damage, which was declared a pandemic by WHO. Corticosteroids may modulate immune-mediated lung injury and reducing progression to respiratory failure and death. The Randomised Evaluation of COVID-19 therapy (RECOVERY) trial is a randomized, controlled, open-label, adaptive, platform trial comparing a range of possible treatments with usual care in patients hospitalized with COVID-19. The method used was to compare dexamethasone six mg given once daily for up to ten days vs. usual care alone. The primary outcome was 28-day mortality. 2104 patients randomly allocated to receive dexamethasone were compared with 4321 patients concurrently allocated to usual care. Overall results showed that 454 (21.6%) patients allocated dexamethasone and 1065 (24.6%) patients allocated usual care did within 28 days. Dexamethasone reduced deaths by one-third in patients receiving invasive mechanical ventilation, by one-fifth in patients receiving oxygen without invasive mechanical ventilation, but did not reduce mortality in patients not receiving respiratory support at randomization. Hence, In patients hospitalized with COVID-19, dexamethasone reduced 28-day mortality among those receiving invasive mechanical ventilation or oxygen at randomization, but not among patients not receiving respiratory support. 


S. Arin Natania, 

Sarvesh Sabarathinam 

SRM College of Pharmacy, SRM IST, Kattankulathur, Chennai.

It will be great, if you share your view on above write-up. 
Axoltol Limb regeneration in humans: How can Science jump from Dreaming fantasy to reality?

Arin Natania. S

Axoltol Limb regeneration in humans: How can Science jump from Dreaming fantasy to reality?

Admin Login by RSP

Admin Login by Center Team

Dear Visitors !

Articles written by authors are their views and their presentation of ideas and knowledge. CHEARS does not claim right on write-up and authors are the real owner and are responsible for their write-up or views. Posts from CHEARS News Room are interpretations or presentation of news from various news resources. 

Posts from executive committee members are posts from CHEARS Office.  

© Center for Health Education, Awareness Resources and Services

Subscribe to Our Newsletter